1st Workshop on Holistic Analytical Technologies for systems Biology Studies

30 October
8:15 - 9:15 Registration
9:15 - 9:30 Opening G. Theodoridis
Presenation of the Bioanalysis Network AUTh
9:40 - 10: 50 Introduction to Systems Biology

Moderator G. Theodoridis

M. Arsenakis, Head of Biology School, AUTh
Introduction to Systems Biology

A. Tsaftaris, INA, CERTH & AUTh
From genetics to epigenetics

S.Tsoka, Kings College UK
Unraveling the function, evolution and interactions in metabolic pathways through systems biology

10:50 - 11:05 Coffee Break
11:05 - 13:00 Metabonomics/ Metabolomics: Introduction

Moderator Ian Wilson

Ian D Wilson, AstraZeneca UK
Systems Biology Introduction: From targeted to non-targeted profiling
“LC-MS and NMR for metabonomic investigations”

John Shockor, Waters, USA
Employing Ion-Mobility Mass Spectrometry for Lipidomic Studies

Discussion

13:00 Lunch Break
14:20 - 16:20 Metabonomics/ Metabolomics:
MS technologies I

Moderator Elwin Verheij

Elwin Verheij, TNO, Zeist ,The Netherlands
Janus: the two faces of metabolomics

Steve Fischer, Agilent, CA
Metabolomics Analysis of Phaseolus vulgaris L. Affect on a Breast Cancer Rat Model with Compound Identification Using an Accurate Mass Retention Time Library

Discussion

16:20 Coffee Break
16:35 - 17:45 Metabonomics/ Metabolomics:
MS technologies II

Moderator G. Theodoridis

Henri Snijders, Applied Biosystems Europe
Novel LC/MS workflows in lipidomics
“Advanced LC/MS Tools to understand Small Molecule Biomarker patterns in targeted and non targeted Metabolomics”

Liz Want, Imperial College London
LC-MS applications in metabonomics

Round Table discussion

31 October
9:00 - 11:00 NMR Profiling

Moderator Emmanuel Mikros

Elaine Holmes, Imperial College London
“NMR based metabonomics”

Emmanuel Mikros, Athens University
NMR profiling studies

11:00 - 11:15 Coffee Break
11:15 - 13:00 Moderator Maria Klapa Maria Klapa, FORTH, Patras, GR
Standardisation of GC-MS metabolomic profiling

Michaela Scigelova, Thermo Fischer
Overview of MS-based protein quantitation methods
“Precision -Omics: The Importance of Being Highly resolved and How Accurate. Is Accurate Enough?”

13:00 Lunch Break
14:00 - 16.00 Proteomics

Moderator S. Garbis

S. Garbis, Bioacademy Athens
The use of quantitative proteomic methods for the simultaneous analysis of potential protein biomarkers and their post-translational variants in breast and prostate cancer research

Mark McDowall, Waters, USA
A High Definition Proteomics Strategy - from Global Discovery via Hypothesis Driven Research to Statistically Rigorous Results

A. Tsarbopoulos, University of Patras, GAIA Research Center
“Role of Mass Spectrometry in the Analysis of Post-Translationally Modified Proteins”

16:00 - 16:30 Closing session Conclusions, Perspectives (Organisers and moderators)
16:30 Coffee, Farewell drink